Archive for November, 2011

Avastin Breast Cancer Approval Withdrawn

Wednesday, November 30th, 2011

avastin 300x231 Avastin Breast Cancer Approval WithdrawnThis week, the federal Food and Drug Administration announced its withdrawal of approval for Avastin, a commonly-used breast cancer drug.

Avastin, the trade name for the drug bevacizumab, is one of a class of drugs known as “biological therapy.” The drug is a product of Genentech, a biotechnology company based in San Francisco, California.

Avastin is designed to inhibit or prevent the growth of blood vessels which feed cancerous tumors, thus inhibiting or even reversing the growth of the tumors themselves. The drug itself is an antibody, which binds to a specific protein known as vascular endothelial growth factor A. This protein is important in blood vessel growth and development in the human body.

The drug thus works through a process known as anti-angiongenesis. Cancerous tumors over-produce VEGF, which then works to form blood vessels connecting to the tumor, so that the tumor can receive nourishment and grow. The process was developed by Judah Folkman, a recently-deceased surgeon with Harvard Medical School.

Although the process took a long time to gain credence, there are now at least 10 drugs utilizing anti-angiongenesis sold in the United States, and industry reports reveal that roughly 50 more such drugs are in the development pipeline.

The FDA’s revocation does not extend to Avastin’s other approved uses. The drug is still approved for the treatment of metastatic colorectal cancer, advanced non-small-cell lung cancers, gliobastoma which has spread even after prior treatments, and certain metastatic kidney cancers.

The FDA’s decision to revoke Avastin’s approval for breast-cancer treatment is based upon what is, to our drug injury attorneys, a particularly troubling combination: lack of effect and dangerous side effects.

First, the drug in fact has no effect on breast cancer. Despite some initial slowing of the growth of breast cancer tumors, patients treated with Avastin did not have an increased survival rate, or live longer, than patients not treated.

Second, the drug triggers a number of extremely serious side effects.

Indeed, roughly 1% of Avastin patients died not from breast cancer, but from side effects of Avastin. These side effects include (among others) heart attacks, strokes, and congestive heart failure.

Moreover, the company was hardly unaware of the concerns which triggered the removal of approval, even as it continued to market and sell the drug as a breast cancer treatment. Even from the early days of the drug’s approval, there were many questions concerning whether the drug had any meaningful effect on breast cancers. In fact, when the drug was approved, it was despite the 5-to-4 recommendation against approval by an advisory panel. Although the FDA considers the recommendations of its independent advisory panels, it is not bound to do so.

Studies since have simply confirmed what many researchers were already saying: Avastin does not improve patients’ chances of survival, or prolong patients’ lives.

The move to revoke the approval began in July of 2010, when a second advisory panel recommended withdrawal based on further studies showing no benefit. But it took until December of 2010 for the FDA to take any action to begin the withdrawal – action that was fiercely challenged by Genentech. Yet another advisory panel conferred, and took testimony on the matter for two days, eventually voting unanimously to revoke the approval – a vote which did not occur until June of this year.

Our personal injury attorneys are appalled that, even with the overwhelming evidence that Avastin was costing lives, not saving or prolonging them, the company continued to actively market and sell this drug, under the FDA’s approval. There is no excuse for a bureaucratic process lasting nearly a year and a half before this confirmed dangerous drug could be withdrawn.

If you have any questions about a possible serious injury or wrongful death claim, please give us a call us at 312-527-4500 or email us at info@passenlaw.com for a complimentary consultation. You can also learn more by following us on Twitter, reviewing our LinkedIn or Avvo.com pages, and by reviewing our website.

Common Missed Diagnoses

Monday, November 28th, 2011

It is likely that you or someone you know has experienced this scenario: you go to the doctor’s office with a list of symptoms, and are sent home with no diagnosis, or told you have “a virus” – but rest does not help. It is possible that the reason you are not improving is because our physician has failed to diagnose the condition causing your symptoms.  This failure to diagnose can be harmless, with the patient recovering in her own time.  However, as our medical malpractice attorneys know only too well, it can also be deadly, robbing the patient of precious days, weeks, months, or even years of treatment — and leading to irreversible permanent injury or death.

For this reason, about forty percent of medical malpractice cases involve the failure to diagnose a patient’s condition.  Because medical malpractice cases are extremely difficult and expensive to pursue, most cases involve catastrophic injury or wrongful death.  Accordingly, the most commonly misdiagnoses conditions in the United States include failure to diagnose heart attack, breast cancer, lung cancer, colon cancer, and appendicitis.

As another example, experts estimate that 10 to 15 million people in the United States have undiagnosed latent tuberculosis.  This condition can be treated and eliminated with antibiotics while the patient remains healthy, but can be much harder to treat if left unchecked, and can even be fatal.

Other commonly undiagnosed conditions include:

  • Sexually-Transmitted Diseases
  • Toxoplasmosis
  • Otosclerosis
  • Osteoporosis
  • COPD
  • Chronic lower respiratory disease
  • Migraine
  • Thyroid problems
  • Parkinson’s Disease
  • Macular degeneration
  • Aneurysm
  • Hemochramatosis
  • Glaucoma
  • Cryptosporiosis
  • Celiac Disease
  • Narcolepsy

If you have any questions about a possible medical malpractice claim, please give us a call us at 312-527-4500 or email us at info@passenlaw.com for a complimentary consultation. You can also learn more by following us on Twitter, reviewing our LinkedIn or Avvo.com pages, and by reviewing our website.

Your Rights When a Drunk Driver Strikes

Saturday, November 26th, 2011

drunk driving accidents Your Rights When a Drunk Driver StrikesWho Is at Fault?

This may seem like an obvious question: the drunk driver whose careless driving caused injury to another is, of course, at fault.  However, others may be legally accountable as well.

For instance, if the drunk driver was a minor, or was served alcohol while visibly intoxicated, you may have a cause of action under the Illinois Dram Shop Act against the bar, restaurant, or club which served alcohol to the driver.  Dram Shop cases are subject to certain limitations- including time limits and liability caps.

If the drunk driver was in the scope of his employment at the time of the accident, you may also have a cause of action against his or her employer.  This is what is referred to as “respondeat superior” or “vicarious liability.”

There may be others who share responsibility as well, which is why it is important to speak with an attorney experienced drunk driver injury lawyer.

Financial Recovery

In many cases, the victim of a drunk driver can recover what are knows and “economic” and “noneconomic” damages. Economic damages are concrete, out-of-pocket costs: past and future medical bills, lost wages, decreased earning potential, and others. Noneconomic damages are less concrete, including things like emotional distress, pain and suffering, humiliation, loss of reputation, and even, at times, inconvenience.

The rights of drunk-driving victims extend beyond those of typical personal injury plaintiffs, as well. In most cases, drunk driving is not simply negligent – it is reckless or intentional. On this basis, the victim of a drunk driver can often seek and recover punitive damages – an award by the jury above and beyond economic and noneconomic damages, designed to punish the drunk driver and to deter others who might otherwise drive drunk.

You may also be able to recover under your own auto insurance policy under what’s referred to as uninsured motorist (UM) or underinsured motorist (UIM) coverage, in the event that the drunk driver is either uninsured or has an inadequate insurance policy.

What to do After the Accident

Many of the most important steps in pursuing legal action against the drunk driver who injured you should take place before you have had a chance to speak with a top car accident attorney like those at Passen Law Group.

First and foremost, after an accident you should seek medical attention immediately. Some very serious injuries – including traumatic brain injury, neck injuries, and spinal injuries – can have symptoms that may develop immediately, or may take days to develop. Likewise, psychological injury from the crash, such as anxiety problems, fear of driving, and depression, can take days, weeks, or months to develop. If you experience these problems, seek medical attention.

Second, preserve any evidence of the crash. Get the driver’s contact information, insurance information, and vehicle information. Even if the drunk driver admits liability at the time of the accident, you can expect him or his insurance company to contest liability later. So, take down the name (double checking the spelling) and phone number or numbers of every person who saw the accident – do not rely on the police to do this for you.

Third, preserve evidence of your injuries and damages. Take pictures of any visible injuries, both initially and as they heal. Take pictures of your car, before it is repaired. If possible, take pictures of the other car, as well. And, if you were a pedestrian or cyclist struck by a drunk driver, take a picture of yourself at the accident site in the clothing you were wearing, and preserve your clothing in its original condition

Finally, report the accident to the proper authorities and to your insurance company. Do not, however, discuss the accident with an insurance adjustor for the drunk driver.  An insurance adjustor is not an independent investigator – it is her job to try to defeat your claim. The best and easiest way to prevent this is to decline to speak with her. Additionally, do not sign any forms for the driver’s insurance company, including medical authorizations – you are not legally obligated to do so, and signing is almost never in your best interest.

These tips and information can help to get you started. But it is only a start. If you or someone you love was injured by a drunk driver, you will also need to speak with an experienced attorney, as soon as possible. Your attorney can counsel you on your options, help you decide how to proceed, and ensure that you do not miss key deadlines for the claims you want to file – often a key point in drunk driving cases.

Please give us a call us at 312-527-4500 or email us at info@passenlaw.com for a complimentary consultation. You can also learn more by following us on Twitter, reviewing our LinkedIn or Avvo.com pages, and by reviewing our website.

Television Falls and Childhood Injuries

Thursday, November 24th, 2011

TV fall injuries Television Falls and Childhood InjuriesIn the past month, two Chicago lives have been claimed in a tragic accident involving a falling television. In the most recent incident, a 3-year-old girl was killed when she was struck by a falling TV in her South Chicago home.  The other victim was a six-year-old boy who was struck by a 32-inch television in the basement of his home in Arlington Heights.

Both children sustained massive traumatic brain injuries, from which they died.

Sadly, this accident was not isolated. In fact, around 17,000 children are taken to emergency rooms each year in America because of heavy or unstable furniture – including televisions – falling on top of them. The current rate is a 41 percent increase over the rate two decades ago. And nearly half of all these injuries are from televisions.

Our law firm is no stranger to these type of injuries.  In fact, Stephen M. Passen of Passen Law Group secured a $19 million jury verdict on behalf of a 9-year-old boy who sustained traumatic brain injuries when a TV fell onto his head in an unsupervised classroom of a private school in Chicago.

Unsurprisingly, the increase in this rate of injuries correlates perfectly with the increase in the popularity of larger and flat-screened televisions. At the same time, Americans moved towards narrower entertainment centers and stands to match the flatter televisions. But narrower stands and entertainment centers are also less stable.

In many cases, children escape from falling furniture with only minor injuries. But about 3 percent of victims require hospitalization. Many of those suffer head and neck injuries – often leaving them with permanent brain injuries or paralysis. And around 20 children die from these injuries each year.

The increase in the rate of injuries in recent years has been despite efforts by industry and regulators to combat the problem. In 2004, ASTM International (previously known as the American Society for Testing and Materials) issued new voluntary manufacturing standards designed to prevent furniture from tipping over. In 2005, Congress considered legislation setting standards for furniture that “poses a substantial risk of tipping” or which contains a glass pane or surface. It died in committee in 2005, then again in 2007. As of today, no government standards requiring testing, safety straps, or anchor mechanisms have been put in place.

But while certain designs are inherently flawed, in many cases there is only so much that even the best designs have accomplished. Researchers at the University of Pennsylvania found in 2006 that flat-panel televisions were weighing in at 100 pounds or more, but with a thin design that is inherently unstable. Americans then expect these devices to balance on lightweight stands, or hang from wall brackets.

How to Protect Your Children

How can you protect your children from this type of injury? First, use extra care, particularly when children are younger: three-quarters of the children injured by falling televisions and other furniture are under the age of six. According to the Center for Injury Research and Policy at Nationwide Children’s Hospital, children under six “simply don’t recognize the danger of climbing on furniture.”

Second, double-check your method of displaying your flat-screen. Use only stands rated for your television model and size, and choose a heavier, larger stand when possible. If you choose to wall-mount your flat-screen television, have the installation professionally done.

Parents and other caregivers can also take physical precautions to prevent injuries. Those with small children in the house should secure all heavy furniture, particularly top-heavy furniture and televisions. Other safety steps include:

  • Place televisions close to the ground, and towards the back of any stand or supporting furniture.
  • Use safety straps or L-brackets to secure televisions and other heavy furniture to the wall.
  • Select only furniture with solid bases and wide legs.
  • Install drawer stops, and place heavier items in lower drawers.
  • Never place enticing items like toys, remote controls, etc., on top of heavy furniture or televisions: this only encourages children to climb.

And then there is the most important precaution of all: supervise young children at all times. If your child spends time in the care of others, inspect the premises and demand that televisions and other large items be secured. Televisions in day cares can fall just as easily as those at home – last year, an unsecured television in an Indiana day care broke the cheeks, nose, jaw, palate, and eye sockets of a two-year-old girl when it fell. She needed multiple reconstructive surgeries simply to regain a functional face.

If you have any questions about a possible serious injury or wrongful death claim, please give us a call us at 312-527-4500 or email us at info@passenlaw.com for a complimentary consultation. You can also learn more by following us on Twitter, reviewing our LinkedIn or Avvo.com pages, and by reviewing our website.

Legislation to Allow Heavier Trucks on U.S. Roadways

Tuesday, November 22nd, 2011

Earlier this year, Senator Olympia Snowe, a Republican from Maine, introduced the Commercial Truck Safety Act.  Despite its name, the bill is designed not to increase safety, but to decrease it. Snowe is the ranking member of the Senate Committee on Small Business and Entrepreneurship, as well as a senior member of the Senate Committee on Commerce, Science, and Transportation – the committee which oversees trucking safety issues. Unfortunately, in this bill her pro-trucking, anti-safety leanings are more than evident.

The bill’s stated goal is to eliminate “inequitable government regulation” which currently keeps heavier trucks off of many Interstate highways. In introducing the bill, Snowe  referred to the nation’s unemployment rate and struggling industrial towns, but made no reference to how she believed that placing heavier trucks on more U.S. highways will increase safety.

Under the current state of the law, trucks weighing above 80,000 pounds are not permitted on Interstate Highways. But 27 states have been granted permanent exemptions to the rule, allowing trucks of up to 100,000 pounds.

If the Commercial Truck Safety Act is passed, states will no longer need to seek individual exemptions to the 80,000 pound weight limit from Congress. Instead, states could simply ask the Secretary of the U.S. Department of Transportation to grant a permanent waiver to the restriction. The Secretary of Transportation (currently Ray LaHood) could then create a three-year pilot program eliminating the weight limit.

A “safety committee” would report to the Secretary at the end of the three-year period, together with a recommendation of whether to reinstate the weight limits. But the decision would rest entirely with the Transportation Secretary.

Whatever the pretensions of the bill’s supporters, it is clear what the outcome will be once this process has begun. After three years of unlimited access to Interstate highways for heavier trucks, the trucking industry will argue that it would be far too costly to return to previous restrictions. Our trucking accident attorneys know that once removed, the current weight limits will be gone for good.

But we also know that heavier trucks are more dangerous trucks. The heavier a commercial truck is, the harder it is to control, the more likely it is to be involved in an accident, and the more devastating the accident.

If you have any questions about a serious truck accident, please give us a call us at 312-527-4500 or email us at info@passenlaw.com for a complimentary consultation. You can also learn more by following us on Twitter, reviewing our LinkedIn or Avvo.com pages, and by reviewing our website.